Diphenhydramine (DPH, Benadryl): What You Need To Know

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Diphenhydramine is a antihistamine allergy drug that, when used in large amounts, provides sedative and deliriant effects. The experiences it provides are normally uncomfortable.

Diphenhydramine = DPH; Nytol; Sominex; Benadryl

Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/4elsdc/diphenhydramine_dph_benadryl/

PsychonautWiki Page: https://psychonautwiki.org/wiki/Diphenhydramine

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    Popular Comments:

Lexi Singz . 2019-05-22
I took Benadryl for an allergic reaction like 10 minutes ago and I looked it up cause I started feeling weird. Is it supposed to work that fast?
121 2 . Reply
stretch . 2019-05-20
Me: takes a handful of benadryl. Also me: searches benadryl high later.
121 2 . Reply
AgenteET786 . 2019-05-20
I know it has an apphinity to D1 receptor
121 2 . Reply
Devin Lunceford . 2019-05-20
My first time on diphenhydramine

I took about 600 mg (didn’t kick in for 40 minutes)
I was sitting on the couch and I seen cockroaches in a dark corner of the room and it being an apparent with roaches I didn’t think anything of it until I turned on the light and they disappeared
Around 3:
I remember looking at the bed and seeing my friend that wasn’t there I would be talking to him and he was just sitting there and I asked if he was good and he disappeared
Around 3:30
I was smoking a cigarette.... I looked at my hands and there was a lit cigarette and when I went to puff on it it would disappear and I kept doing this
I looked next to me and seen my two buddy’s and I was talking to them about 30 minutes and I felt like my eyes was open and I seen them but my eyes was closed and when I actually opened my eyes they disappeared
Around 4:50
I started to see a black figure running back and fourth throughout the halls and I knew If was the sleep aids so I didn’t pay attention to it despite the fact I’m paranoid and scared
Around 6
I walk in his living room and I’m talking to by buddy’s mom and I puffed on another cigarette and it was gone and I was like I dropped a cigarette on the couch and I was looking for it and he said you didn’t drop a cigarette
Around 6:40 I’m tired and I want to sleep but can’t
I layed down and fell asleep and I don’t remember anything after that
121 2 . Reply
Wolfgang . 2019-05-19
1:58 He’s not mewing
121 2 . Reply
leepinlepin wingadingdong . 2019-05-17
Talk to your doctor if your delirium lasts more than 4 hours.
121 2 . Reply
Ernest Isaac . 2019-05-15
I had terrible sleep problems for 2 years and thought I was hopeless, nonetheless by using this sleep solution “Yοyο Fawam” (Google it), I`m sleeping normally once again and also REALLY LIKE sleeping. This is a product that you should not pass up. I believe it is too great to be real in the beginning however since I have used it, I started to be the product’s primary believer.. .
121 2 . Reply
Andrew Winters Bell . 2019-05-14
I can taste the pills in the back of my throat. Not a good feeling. Haven’t done it in a couple of years. I plan on continuing not to do it.

If I wanna OTC I’d take Dextromethorphan.
121 2 . Reply
Brennan Archives 2 . 2019-05-10
This is on my top 5 drugs ive tried tbh, i just dont like taking it before bed because the restlessness keeps me up. Im keeping the dosage under 450 every time i do it though bc the first time i did it i took an entire box (600mg) and was just extremely uncomfortable, delirious and threw up. Only bad experience ive had on it but i imagine its a personality based drug
121 2 . Reply
Waco馬鹿 . 2019-05-09
I'm gonna take 450mg because I hate my life
121 2 . Reply
Mike Hunt . 2019-05-07
I tried 400mg really bad muscle cramps. It's nothing compared to acid. Please don't try it even if you're desperate to take drugs.
121 2 . Reply
Christian C. . 2019-05-06
The drug from hell!! often taken it unknowingly as its an ingredient in many over the counter cough syrups... But every-time it produces the same effect. I become restless and tired at the same time,very irritable, miserable, gloomy depressed and sometimes even aggressive... Now I've sworn to refuse it from my doctor and check that it's not present in nasal decongestants or cough syrups.
121 2 . Reply
Bill Gotti . 2019-05-05
Sedated/restless effects... I'm confused. Is this like when you take xanax and you cant open your eyes or walk a straight line but you cant stop bouncing off walls and breaking into cars? Lol
121 2 . Reply
0kewl . 2019-05-04
I looked this up because it made me late for work. My sister said it would help me sleep, but it knocked me out for like 12 hours. I woke up an hour after I was supposed to be at work.
121 2 . Reply
lil ice . 2019-05-02
I got half my school on it, was good a time, it would make my mouth hella dry, I wouldn't talk to anyone because I felt so lazy to talk, 9 was always good to take, but way back then I was popping 18-20 pills
121 2 . Reply
OSoftSoda . 2019-04-30
I did a 1250 mg dose and jumped off a roof. Pretty lit
121 2 . Reply
Jon Iwanyszyn . 2019-04-27
I remember constantly redosing this when trying to treat restless legs and arms. It made it exponentially worse. I nearly chewed my own arms off.
121 2 . Reply
Oliver Hunter99 . 2019-04-27
I don’t wanna make this too long but my trip was the scariest thing i’ve ever experience and went to therapy for it .. My dad passed away a while ago and my dumbass decides to take 1000 mg or a little bit over the a couple weeks after his death Next thing u know he appears in my room and I remembered clearly having a conversation about School and how he survived the car accident... I wake up in my room surrounded by family and my mom tells me that i was talking loudly to a stuffed spongebob pillow for about 2 hours ... Worst experience of my life
121 2 . Reply
fireandcopper . 2019-04-26
I had a major panic attack with Gravol and weed. Never again
121 2 . Reply
T-B4NE . 2019-04-22
I sadly od took 38 Benadryl , i had saw freinds that wernt there heard demon voices was first affect , i saw spiders everywhere to thousands scorpions . ghost like things i had saw , ace mussles an hurt they felt bad . it was a bad experience i had sleptp for 50 ish hours . grandparents hadent took me at the hospital at that point i was 16 at that time . my lip had swelled 6 times the size as it was . so had to go to the hospital at this point it mentally mess me up took me 7 months to think normal an it was a bad experience. Dont take it to get high . this was my bad experience with Benadryl i know i wasnt very smart . i was very lucky to woke up .
121 2 . Reply
Galvanized Dreamer . 2019-04-20
This greatly explains its common reference is the Breakcore scene.
121 2 . Reply
Brian Cee . 2019-04-20
I take half a pill to sleep.
121 2 . Reply
Otto Lotto . 2019-04-19
I I’m high from weed and take a 25mg of benadryl????
121 2 . Reply
smoothhaha23 . 2019-04-16
I take this every nignt to go to sleep does this drug have withdrawls?
121 2 . Reply
Cj Bray . 2019-04-15
Just took 500, mg. now we wait!
121 2 . Reply
Thaspacegoat Æ . 2019-04-14
This is a drug for real men. Back in the day me and my Bois refered to it as fucking "spider city" man. We'd play some wicked games that included taking a 550 mg dose and whoever got paranoid first had to go to the 700 club the next day. Mixing it with alcohol and dxm was real fuckin wild, music enhancement was fuckin wicked. I don't fuck with this shit anymore because I now have hppd from it and hear voices here and there but not frequently. Do it with friends and it's amazing, trip on it with a buddy (500 or under) and have a sober friend who's just smoking weed or drinking but not getting blackout.
121 2 . Reply
Janos K . 2019-04-13
SethAFitzgerald kindly list your qualification to present this information, are you a chemist or a journalist perhaps?
121 2 . Reply
Twa Xebza . 2019-04-11
2:44 That dude's smile tells you all about this drug haha
121 2 . Reply
Antispaghetti God . 2019-04-10
If you're going to do it at higher doses and are male, know this will kill your boners for up to a week, the trips aren't bad though just got to stay calm
121 2 . Reply
Translucent Grail . 2019-04-10
Benadryl is placebo, for me anyway, it doesn't help with sleep even at high doses. Never expected to hear about people abusing it lol sweet vid.
121 2 . Reply
Edray13 . 2019-04-06
The information suggesting this is a proper suicide drugs shouldn't be as easily assecible as the drug itself. It could save life(mine) from doing things in the spur of the moment of out desperation.
121 2 . Reply
Edray13 . 2019-04-06
I used this drug for a failed suicide last year and can say that 3gs did not kill me,but using it for anything other than sleep is fuckin stupid. I will never be coaxed into doing that again.
121 2 . Reply
Nice Guy . 2019-04-06
Fuck all that "spiders and bugs" shit. I get high from just two pills. Drink a coffee and you won't get sleepy. Less is more people. Talk to your doctor before fucking with this.
121 2 . Reply
lkjyuiop . 2019-04-06
Drink beer with it and you will get fucked up
121 2 . Reply
Abserd O . 2019-04-05
The constant feeling of having to piss is absolutely fucking brutal.
121 2 . Reply
Jake Provniiik . 2019-04-05
Idk if you guys in the comments are just capping hard or what. I used to take Benadryl alongside Cetirizine when I was sick. Ceririzine for my allergies and Benadryl because my mom thought it was appropriate.

I took 14 Benadryl tablets in the span of 10 minutes. (50mg) because I was a dumbass.

Literally nothing happened, at all.
121 2 . Reply
Mari Christian . 2019-04-05
Call me naive but I usually take 25mgs of Benadryl for an allergic stuffy nose. Once I was given the same dose to prevent an allergic reaction when I had a blood transfusion in a hospital. However, I was both fascinated and repelled by the risky business of taking it for hallucinogenic purposes.
121 2 . Reply
Jon Harris . 2019-04-04
Why does this video start with the downsides of getting high and not start with information about the normal use of the drug?
121 2 . Reply
Dante Alighieri . 2019-04-04
I can't even take the recommended dose. If you suffer from RLS (restless leg syndrome) it can send it into overdrive.
121 2 . Reply
diggythedog . 2019-04-03
I took 8 of 25g before school noticed side effects I was staring at a wall for 25 mins umm when I was doing my work I saw Elmo one time and I got confused alot:]
121 2 . Reply
Kringe Stick . 2019-04-03
So im not planing on using this drug habitually to trip or hallucinate but more for the very calming affect that it has on my body when I take 100-175mg. since I don't have regular access to weed or any other type of drug, would taking 100-175mg say 2-5 times a month to relax be ok and safe, if not what type of things will I experience and is there any I can use benadryll recreationly in a good way
121 2 . Reply
Kringe Stick . 2019-04-03
So im not planing on using this drug habitually to trip or hallucinate but more for the very calming affect that it has on my body when I take 100-175mg. since I don't have regular access to weed or any other type of drug, would taking 100-175mg say 2-5 times a month to relax be ok and safe, if not what type of things will I experience and is there any I can use benadryll recreationly in a good way
121 2 . Reply
chris cameron . 2019-04-02
i take 5 dihenhydrimine almost everynight
121 2 . Reply
chris cameron . 2019-04-02
I took 15 50mg diphenhydramine pills and I didn't hallucinate but I almost had a heart attack!
121 2 . Reply
Norie Holley . 2019-03-30
this drug is only safe up to 400mg/day and any amount over 50mg does bring me vivid hallucinations.
121 2 . Reply
ryan . 2019-03-29
im scared that i got dementia from using it so much when i was a teen
121 2 . Reply
Red_Doggo . 2019-03-28
This stuff is like real life fear toxin.
121 2 . Reply
Toper H . 2019-03-26
This is the shit thats in unisom sleep gels 50mg they love that shit in Melbourne Australia mixed with heroin its the shit you don't wanna fuck wit
121 2 . Reply
Alex Hand . 2019-03-25
I had a girlfriend who would pop 5 benadryl to go to sleep. I figured if she did that it would be safe for me to take 2-3. I woke up a couple hours later unable to stay awake, unable to go to sleep. I was stuck in a twilight state. I could stand up but not walk straight, my eyes couldn't stay all the way open, and I would get huge rushes of energy that would get stuck in my muscles like restless leg syndrome all over my body. I took Benadryl another time and the same thing happened. I'll never take it again.
121 2 . Reply
Ev3rsonix . 2019-03-22
Oddly enough I liked the recreational effects of this drug more than dxm bc no matter how much dxm I took I didnt seem to do much while this got me pretty fucked up
121 2 . Reply