The Science of Anti-Vaccination

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Fewer children in the United States are getting vaccinated. That’s bad news for those kids, and also for public health in general. Often, the response is to argue and debate and get angry at people who are we see as making terrible, irrational decisions. Instead of doing that, let’s use science to understand why this is happening in the first place.

Hosted by: Hank Green
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Meta-Analysis of the Safety of Vaccines: http://pediatrics.aappublications.org/content/134/2/325
The Internet and the Psychology of Vaccination Decisions: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19849
Naturalness Bias: http://www.ncbi.nlm.nih.gov/pubmed/18319507
Omission Bias and Vaccines: http://mdm.sagepub.com/content/14/2/118
Difficulty in changing minds once they’re made: http://pediatrics.aappublications.org/content/early/2014/02/25/peds.2013-2365
Onset Patterns of Autism: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857525/
Bad is Stronger than Good - Negativity Bias: http://assets.csom.umn.edu/assets/71516.pdf
Parental Vaccine Decision Making: http://www.ncbi.nlm.nih.gov/pubmed/24011751
Read more about Risk Perception: https://en.wikipedia.org/wiki/Risk_perception
And Explanatory Style: https://en.wikipedia.org/wiki/Explanatory_style

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Tags :

vaccines vaccinations anti-vaxxers autism autism spectrum disorder psychology social psychology cognitive psychology cognitive bias negativity bias confirmation bias explanatory attribution pattern recognition risk perception cognition science hank green sci show Vaccine Controversies Vaccination (Field Of Study) Vaccine (Drug Class)

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    Popular Comments:

Wake Up! . 2019-02-22
1. Tip: slow down and breathe. You talk waaaaay too fast. Massive information is lost.
2. Autism is not a "disease" (Degenerative) but rather congenital (present at birth)
3. Although it is true the bogus research that connected vaccines to autism and the disgraced doctor was found out, with the new field of epigenetic's, they are getting closer to showing that the preservative in question, thimerosal DID "flip the genetic switch" at the epigenetic level bringing forth a new phenotype because the genotype was changed! Genetics 101!
121 2 . Reply
George Tryfonos . 2019-02-22
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nathan massell . 2019-02-22
Parents are allowing nature to take its course! Hahahahaha exactly
121 2 . Reply
Saaman K . 2019-02-22
This video itself is a great example of confirmation bias. Without going into facts or addressing arguments from people who don't want to vaccinate, he just assumes vaccines are safe and ignores all 100+ independently peer reviewed studies that do suggest a link between autism and vaccines, then proceeds to do explain about the same cognitive biases that made this video possible.
121 2 . Reply
media . 2019-02-22
this presenter is a child abuser and they look liek they were born a female, not a male.
they look like a trans
they tell lies to promote the harm of chldren,
121 2 . Reply
paytyler . 2019-02-22
PEG has been linked to Autism, which is often used to cut drugs or as a tabletting agent.
121 2 . Reply
VoidKitty . 2019-02-22
I wish I could like this video more than once. The antivax movement is very dangerous.
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The Crook . 2019-02-22
The pharmaceutical companies create customers not cures.
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Cole Towner . 2019-02-22
As someone who has diagnosed with high-functioning autism, I firmly believe it is a disorder that can cured for the most part in certain circumstances. In my case I was one of cases that would fling their arms up and down from time to time and I even stopped speaking for for two years in between the ages of 1 and 3 and a half years old. Now I'm 18 years old and with the help of therapy and medication I I am considered by most as normal and don't appear autistic in any way aside from the lack of social ability. Even then that only consists of having trouble starting and continuing on with conversations, but if its a topic I'm knowledgeable on or have interest in I don't really have an issue continuing it once it started though.
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Dogs Sing . 2019-02-21
They are INTENTIONALLY poisoning modern vaccines to create a massive disease vulnerability in the population. They're trying to engineer a mass plague by undermining the vaccines we NEED with Mercury and other poisons. When the time is right, they will unleash a manufactured flu that will kill billions.

We must recognize the extreme threat these big pharma corps pose to our HUMAN RIGHT to access untainted, and Mercury free vaccines. We cannot allow these corporations to continue supplying OUR CHILDREN with compromised third world vaccines for profit. Stand up and fight back against GREED.


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DON KILLUMINATI . 2019-02-21
Vaccines cause brain swelling! Vaccine manufacturers are exempt from prosecution if their vaccinations kill anyone, why? Cause they know vaccinations are trash!
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Ginja Ninjaaa . 2019-02-21
The nternet...
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isopod number 15 . 2019-02-21
Autism causes vaccines
121 2 . Reply
Leon Wurth . 2019-02-21
I'm seriously impressed by your ability to look at the situation so objectively.
121 2 . Reply
ricardo machado . 2019-02-21
You talk about scientific studies made by the same people that make the vaccines.
And the inexistence of the true placebo, you should know what it means a placebo, because vaccines don't have a placebo.
And you must be a idiot for saying that parents don't know what to think about the injuries that vaccination caused. And for that I send you some crimes that are committed by the pharmaceutical industry. And no one goes to jail. And all that has FDA approved. You are not for science you are a little sheep.

Vioxx® killed 60.000 humans caused 88,000 to 139,000 excess cases of heart attack and stroke.
Merck paid the federal government a $950 million fine. It has also paid over $4 billion in compensation to victims (or their family members) for the side effects Vioxx® caused, along with punitive damages for covering up the lethal dangers.

Before it was withdrawn, Merck racked up $11 billion in Vioxx® sales

Johnson & Johnson has been ordered to pay $4.7 billions in damages

Propulsid (Cisapride)
Cause for recall:
more than 270 cases of serious cardiac arrythmias (including ventricular tachycardia, ventricular fibrillation, torsades de pointes, and QT prolongation) reported between July 1993 and May 1999, with 70 being deaths.
Propulsid is also banned in India (2011) and available for limited use in Europe. It is still available for use in animals in the US and

PTZ & Metrazol (Pentylenetetrazol) on the market for
Use: Convulsive therapy for schizophrenia and other psychiatric conditions
Cause for recall:
uncontrollable seizures; pulled muscles; fractured bones; spine fractures in as many as 42% of patients..

Raplon (Rapacuronium) on the market for
Use: Non-polarizing neuromuscular blocker (used in anesthesia
Manufacturer: Organon Inc. 1999 to
Mar. 27, 2001
Cause for recall:
bronchospasms and deaths..

Raptiva (Efalizumab) on the market for
Use: Psoriasis
Manufacturer: Genentech 2003 to
Apr. 8, 2009
(completely withdrawn by
June 8, 2009)
Cause for recall:
progressive multifocal leukoencephalopathy (PML; a rare and usually fatal disease that causes inflammation or progressive damage of the white matter in multiple locations of the brain)

Thalidomide was sold in the 1950s and 1960s as a sedative and anti-nausea medication for pregnant women suffering from morning sickness. Studies in mice and other animals had suggested thalidomide was safe and led some countries to allow the drug to be used in humans. By 1961, it became clear that thalidomide use by pregnant women led to serious birth defects, and the drug was removed from the market. By then, thalidomide had caused birth defects in over 20,000 babies and killed a lot more , a tragedy that has been described as the biggest man-made medical disaster in human history. Grünenthal has settled numerous thalidomide lawsuits, and as of 2010 reportedly made 500 million euros in total payments to victims. The number of thalidomide lawsuits continues to increase.

Fenfluramine/phentermine (Fen-Phen)

Wyeth-Ayerst Laboratories
Recalled: 1997 (after 24 years on the market)
Financial damage: Awards to victims close to $14 billion, making it one of the most costly products liability cases in history.

Fen-Phen’s was a hugely popular weight loss drug, its popularity peaking in the 90’s. It is estimated that as many as 6.5 million people took it to help fight obesity. After consumers began experiencing heart disease and other pulmonary problems, the FDA set the recall in motion. American Lawyer reported that more than 50,000 Fen-Phen victims have filed suits against Fen-Phen’s maker Wyeth, and legal expenses combined with awards may have exceeded $21 billion. Lengthy time in the marketplace combined with the severity of both the public reaction and the significant awards granted to its victims make its impact unprecedented.

Diethylstilbestrol (DES)

Maker: Multiple manufacturers (DES was never patented as it was created with British public funds)
Recalled: 1975 (after 37 years on the market)
Financial damage: Steep, but difficult to quantify because each manufacturer paid out legal damages correlated with its respective market share (a new way of awarding damages in these cases).

DES was prescribed for more than thirty years to prevent miscarriages and other complications during pregnancy. It was not until 1971 before it was connected to a rare tumor that kept appearing in the daughters of women who had taken it. The FDA only banned DES prescriptions to women because no such problems have been found in men. In fact, it can still be prescribed to men to treat estrogen deficiency. Litigation over DES led to a landmark products liability award that heavily influenced how both courts and the FDA approach oversight of drugs with multiple manufacturers.

Cerivastatin (Baycol)

Maker: Bayer
Recalled: 2001 (after four years on the market)
Financial damage: Litigation-related damages totaled $1.2 billion

Baycol, prescribed to patients as a treatment for high cholesterol, is reportedly responsible for more than 100,000 deaths and about as many lawsuits. It was connected to a severe muscle disorder known as rhabdomyolysis, which clogs the kidneys with protein from dying muscle tissue.
Etc etc etc etc etc
121 2 . Reply
Amy Sternheim . 2019-02-21
You'd think adult males would be all for the mumps vaccine! LOL If you know about the mumps you'll laugh too!
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Edwin Jewell . 2019-02-21
This guy needs to go back to Science class. Government Vaccines ahh I'll pass.
121 2 . Reply
Obi Wan . 2019-02-21
Me (provax): I hope that antivaxers see this
Antivax: (sees linl on youtube) nah it's big pharma
121 2 . Reply
Skate Or Die . 2019-02-21
I agree with everything, but in defense of stubborn people a cognitive bias could later on be referred as an intellectual breakthrough.
Progress would be slow without opposition. Sadly it's probably wrong in 99.9% of the cases, like on vaccination issues or flat earthers (you know who you are, you're essentially the same). vaccinate!
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Read my description . 2019-02-21
Unvaccintaed kids in the pool

Kid: Marco!

Bacteria: Polio!
121 2 . Reply
bouncer dogsly . 2019-02-21
I am a chemist and have worked for companies like BP. What I know is this. If you have enough money you can buy your self hundreds of scientists to promote whatever you want. Pharma is very big business and if you research the Rockerfella family, you soon realise their history started with a man called Devil Bill. He was the original snake oil salesman, who trot round the US and sell a cures in a bottle, that he claimed could cure everything from baldness to cancer. And of course there are always those who will buy.
And it is these Rockerfellas that are Standard Oil. And as the billions poured in they then took over every medical medical school in the US and all the governing bodies. They launched a campaign against natural cures as quackery so they could push their chemical cures. They were the ones along with others that found a use for a useless bye product of the production of aluminium- Sodium Flouride - a toxic poison. So they got them selves a load of scientists who would promote that Sodium flouride in water and toothpaste would help fight tooth decay and then made billions out putting this poisen in water and many other dental products. It is a FACT that Stalin use flouride in the water at his Gulags because it had a pacifying effect on the prisoners and the gulag required less guards to run.
So BE VERY SCEPTICAL OF SCIENTIST, BECAUSE THEY CAN BE BOUGHT JUST LIKE POLITICIANS. MY MOTHER NEVER HAD ANY OF US VACINATED AND I WAS BORN IN THE 1950S WHEN FOOD WAS NATURAL AND WITHOUT ADDITIVES. I HAVE BEEN IN HOSPITAL ONLY ONCE IN MY LIFE TO GET MY HAND STITCHED UP AFTER A FALL WHEN YOUNG. I get constant letters off my GP in the UK to attend for check ups because I have seen a doctor only three times in my life and that was only for accidental injuries. I am 65 years old and as an Industrial chemist, the first thing I ask a scientist who wants to promote something is, WHO IS FUNDING YOU.
That's why also I am very cynical about climate change as I have studied the origins and believe it is just another money making scam by people like the Rockerfellas.
121 2 . Reply
Adrin Rem . 2019-02-21
Why the crash course guy is in here?? 😂
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Rozann Moake . 2019-02-21
As someone with a vaccine injured child I find people who refuse to acknowledge the problem to be completely close minded and unwilling to do any research.
Do some research. Thousands of parents know that vaccines have damaged their children beyond recognition. They are not crazy. Those who say vaccines are “safe and effective” are either uninformed or dishonest.
There are some vaccines that now have autism as a possible side effect listed on the vaccine inserts.
I certainly hope vaccine numbers go down. It is not confusing to choose to listen to people who have documentation and studies over those who have straw men and studies like the ones you mentioned. Like those that document what causes parents not to vaccinate! That’s not a safety study!!!
FYI, measles wasn’t something people were afraid of getting when people got it all the time. Look at all of the old tv shows that joke about getting the measles!!!
Your show was a lot of talk without saying anything.
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James Meritt . 2019-02-21
Think of vaccines as evolution in action.
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BladeMasterz916 . 2019-02-21
Anti Vaxers should not have to VAX their kids, but if they get sick. We should let them die..... Cant continue to pass on the stupid gene!
121 2 . Reply
Elemis . 2019-02-21
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That Girl Reacts . 2019-02-21
Yeah... They're still dumb tho. 😕
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Cory Davis . 2019-02-21
I like how this guy completely ignores the fact that modern vaccines contain mercury and aluminum, so much for being objective and using science.
121 2 . Reply
aimee Enochs . 2019-02-21
Vacation stop do woser at you job
121 2 . Reply
Ungregistered User . 2019-02-21
We actually do know what causes autism.

You'll notice that everything listed as a possible cause of #autism is something that messes with the #thyroid, or #endocrine system. The most common problem is severe #iodine deficiency during #pregnancy, so areas that don't get much rain do not have much iodine in plants and animals.

“What Causes Autism and Why Are More and More Kids Being Diagnosed With It? | National Center for Health Research”

ℹ️ The title of this link is “Iodine deficiency as a cause of autism - Journal of the Neurological Sciences”
(website has to be viewed as a desktop website to access citation links)
“The recent article by Román proposes maternal hypothyroxinemia as an important cause of autism [7] with which I strongly agree.”

“Maternal hypothyroxinemia can result from a number of different pathways and etiologies, including iodine deficiency. A diet deficient in iodine can result in a wide range of negative effects on the developing fetus, from mild IQ loss to severe mental retardation, i.e., cretinism [8]. There has also been an association between iodine deficiency and attention-deficit hyperactivity disorder (ADHD) [9], another condition that has been increasing in the US [3,10].”

World Health Organization - “Is it true that lack of iodine really causes brain damage?”
Answer (key sentence): “It is particularly important that pregnant women receive enough iodine in their diet, as iodine is a key nutrient in the fetal development process, especially with respect to the brain.”

This link goes to an important paragraph at the US Office of Dietary Supplements.

“What happens if I don’t get enough iodine?”
“... In pregnant women, severe iodine deficiency can permanently harm the fetus by causing stunted growth, mental retardation, and delayed sexual development. Less severe iodine deficiency can cause lower-than-average IQ in infants and children and decrease adults’ ability to work and think clearly.”

You'll be able to find several reliable sources of facts with this search, it'll find reports from medical studies.

“Endemic cretinism includes two syndromes: a more common neurological disorder with brain damage, deaf mutism, squint and spastic paresis of the legs and a less common syndrome of severe hypothyroidism, growth retardation and less severe mental defect.

Both conditions are due to dietary iodine deficiency and can be prevented by correction of iodine deficiency before pregnancy.”

“The Interaction of Agricultural Pesticides and Marginal Iodine Nutrition Status as a Cause of Autism Spectrum Disorders”

You'll be able to find several reliable sources of facts with these two searches.


“Hypothyroxinemia and Pregnancy”
“A lack of thyroid hormone during early fetal life results in irreversible brain damage The detrimental effect of iodine deficiency and maternal hypothyroxinemia on fetal brain development are probably related to reduced maternal T4 transfer to the fetus before the onset of fetal thyroid function.”

That article goes to an article by the “American Association of Clinical Endocrinologists” https://journals.aace.com/doi/abs/10.4158/EP10309.RA
That is also titled: “Hypothyroxinemia and Pregnancy” and one sentence says:
“Studies have demonstrated the pivotal role exerted by maternal T4 on fetal brain development and the negative impact of hypothyroxinemia on neurobehavioral performance in offspring.”

• The previous link has these on the page •
“The maternal iodide pool reduces during pregnancy because of increased renal clearance of iodine and transfer of iodine to the feto-placental unit. This results in an additional requirement of iodine during pregnancy of ~100% as compared to nonpregnant adults. In accordance, the recommended iodine intake in pregnancy is 250 μg/day. A daily iodine intake below this threshold poses risks of various degrees of thyroid insufficiency for both the mother and the fetus.”

“Role of thyroid hormone during early brain development.”

“Influence of maternal thyroid hormones during gestation on fetal brain development.”

“Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development.”

“Iodine supplementation during pregnancy: a public health challenge.”
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kalvin lewis . 2019-02-21
3.6k people got autism from vaccines
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Alec Bussen . 2019-02-20
His argument applies to both sides of the vaccine issue, doesn't address science, but psychology (and not in an unbias way) and ignored addressing: 1) The role American law and pharmaceutical companies play in vaccine propogation (and why people wary of vaccines see this as important). 2) How vaccines may affect the microbiome of children. 3) How many and what types of vaccines are administered (which differ from country to country, though that's not much of a surprise). 4) When vaccines are administered and the relationship of that to the child's immune development. 5) How certain vaccines can affect health in, say, the liver (like I heard a person wary of vaccines say about hpv vaccine goven to children). 6) How and what qualifies as adverse reactions to vaccines in studies. Etc.

Not that he's wrong or right. I just started researching this issue for when my baby comes. But, his argument didn't acknowledge any other bias than the scarecrow argument anti-vaccine group he described (such as his own bias or those with money invested in the pharmaceutical market).

You made an engaging video and look intelligent. But your video wasn't helpful. If you end up doing another video on this subject, could you address and engage the areas of argument from the anti-vaccine side? Thanks!
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Lelrica . 2019-02-20
Just got my Meningococcal vaccine yesterday!💪 I've been doing well thank you, no adverse side affects. Oh look at that, when I was a baby I got a series of vaccinations from MMR, polio, chickenpox vaccine, Hep b, and a few others. I don't have ADD, ADHD, or autism. Wow I wonder why I'm alive?! Have a nice day👋edit 1: I'm still alive, no new allergies, ADD, ADHD, and/or autism thank you. Day three of have had my meningococcal vaccine.
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Ben Stone-Ott . 2019-02-20
You didn’t actually address the science behind anti vaccination. So let me do it for you.
The reason people believe that vaccines cause autism is because of the aluminium that is used as an adjuvant in the vaccine. The idea is that the aluminium increases the effectiveness of the vaccines.
Aluminium can be very harmful to humans if it is injected into the bloodstream because it causes harm to the brain. And the amount of aluminium in vaccines is not safe. This is the safe level of aluminium to be injected according to the FDA .

“Aluminum may reach toxic levels with prolonged parenteral administration [this means injected into the body] if kidney function is impaired . . . Research indicates that patients with impaired kidney function, including premature neonates [babies], who received parenteral levels of aluminum at greater than 4 to 5 micrograms per kilogram of body weight per day, accumulate aluminum at levels associated with central nervous system and bone toxicity [for a tiny newborn, this toxic dose would be 10 to 20 micrograms, and for an adult it would be about 350 micrograms]. Tissue loading may occur at even lower rates of administration.” [Department of Health and Human Services, Food and Drug Administration, Document NDA 19-626/S-019, Federal Food, Drug and Cosmetic Act for Dextrose Injections.]


Many vaccines exceed the 25 micrograms max limit that is recommended by the FDA as shown here

Hib (PedVaxHib brand only) – 225 mcg per shot
Hepatitis B – 250 mcg
DTaP – depending on the manufacturer, ranges from 170 to 625 mcg
Pneumococcus – 125 mcg
Hepatitis A – 250 mcg
HPV – 225 mcg
Pentacel (DTaP, HIB and Polio combo vaccine) – 330 mcg
Pediarix (DTaP, Hep B and Polio combo vaccine) – 850 mcg

And here is the recommended safe amount per weight of baby

8 pound, healthy baby: 18.16 mcg of aluminum

15 pound, healthy baby: 34.05 mcg of aluminum

30 pound, healthy toddler: 68.1 mcg of aluminum

50 pound, healthy child: 113 mcg of aluminum

150 pound adult: 340.5 mcg of aluminum

350 pound adult: 794.5 mcg of aluminum

most children are given the hepatitis B vaccination. The amount of aluminum in the Hepatitis B vaccine alone is almost 14 times the amount that is FDA approved.

There is the the science and I am not suggesting that vaccines should be stopped all together but that they should not use aluminium in the vaccines and certainly not in the amounts that they are in.
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Vitor Leão . 2019-02-20
4:54 And that is why its nearly impossible to convince a believer that god is the creation of a lunatic man who wanted to write a bunch of gibberish to convince people that a fairy tail being created the universe.
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Jonathan steinhardt . 2019-02-20
This is a Theory not a video about real science. Hear is a link to a video that is full of real science and links to all the information he is referencing. Now, dont get me wrong, the man in this link dose have a clear agenda that is bias but the science and links are all there. https://youtu.be/L9S8nE-USrM
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Canned Coochie . 2019-02-20
I swear did these people not learn basic high school biology?
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Ronnie Wurz . 2019-02-19
You go guy
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Alex . 2019-02-19
I was curious, so i just read the information pamphlet from the MMRii vaccine manufacturer. Two of the listed possible side effects include: Brain Damage and Delayed Cognition. So maybe this doesnt fit your definition of "Autism" but it absolutely fits the definition of something i dont want for my children. If you have a problem with this, im happy for you to stay away from our family.
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atc1239 . 2019-02-19
God if only more people watched this back then. These antivaxxers are literally bringing back diseases that no longer existed and that shouldn't exist in a first world
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Vikingbiznitch . 2019-02-19
Forget autism, what about all the other permanent injuries that can occur from vaccinating!? Blindness, seizures and fever bad enough to cause brain damage.... are people with autoimmune diseases more likely to suffer vaccine injury? They're advised not to get vaccines even in adulthood, why? As of now we don't know what risk factors are involved in vaccine injury. Until research and scientific studies can answer these questions parents will still be reluctant.
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Bob Even . 2019-02-19
Let the body fight off what he gets.
Me: your son will live through the Ebola virus?
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srv3fender . 2019-02-19
After you've seen about 10 kids who are perfectly healthy , out of nowhere become autistic on the same day they get vaccinated, you too might think twice
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FutureBerea Alumn . 2019-02-19
Even if vaccines did cause autism, that’s no reason to not vaccinate. Not all anti-vaxxers believe they cause autism. There are actual valid reasons not to vaccinate. Especially if you’ve had a child die from a vaccine reaction.
121 2 . Reply
FutureBerea Alumn . 2019-02-19
Vaccines don’t cause autism, but they can kill.
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Legendary Broly Boi . 2019-02-19
As much as I understand the importance of vaccines, Anti-Vaccine parents have a point. (Even if it’s a small one)

The fact had humans as a species need these vaccinations in order to live past our toddler years is sad. We’ve failed as a species biologically. What happens when medicine is scarce? People will die, but that means that those who DO survive will have children who will be fine without the vaccinations.

The way I see it, they SHOULD be allowed to reproduce. If they loose a few kids, then it’s a risk they were willing to take. But at least the kids who survive have better genetics than all the kids who are practically solely dependent on Vaccines.

Anyways, God Bless!
121 2 . Reply
Simon a Simon . 2019-02-19
It's called none
121 2 . Reply
EloquentTroll . 2019-02-19
We should be charging anti-vaxxers with child endangerment, seriously.
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treverfox . 2019-02-19
Obviously this guy is very biased. Its sickening.
121 2 . Reply