Baroreflex Regulation of Blood Pressure, Animation.

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How heart rate is controlled by the parasympathetic and sympathetic divisions of the autonomic nervous system, with overview of baroreceptor resetting.
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Baroreflex, or baroreceptor reflex, is one of the mechanisms the body uses to maintain stable blood pressure levels or homeostasis. Baroreflex is a rapid negative feedback loop in which an elevated blood pressure causes heart rate and blood pressure to decrease. Reversely, a decrease in blood pressure leads to an increased heart rate, returning blood pressure to normal levels.
The reflex starts with specialized neurons called baroreceptors. These are stretch receptors located in the wall of the aortic arch and carotid sinus. Increased blood pressure stretches the wall of the aorta and carotid arteries causing baroreceptors to fire action potentials at a higher than normal rate. These increased activities are sent via the vagus and glossopharyngeal nerves to the nucleus of the tractus solitarius – the NTS - in the brainstem. In response to increased baroreceptor impulses, the NTS activates the parasympathetic system – the PSNS - and inhibits the sympathetic system – the SNS.
As the PSNS and SNS have opposing effects on blood pressures, PSNS activation and SNS inhibition work together in the same direction to maximize blood pressure reduction. Parasympathetic stimulation decreases heart rate by releasing acetylcholine which acts on the pacemaker cells of the SA node. Inhibition of the sympathetic division decreases heart rate, stroke volume and at the same time causes vasodilation of blood vessels. Together, these events rapidly bring DOWN blood pressure levels back to normal.
When a person has a sudden drop in blood pressure, for example when standing up, the decreased blood pressure is sensed by baroreceptors as a decrease in tension. Baroreceptors fire at a lower than normal rate and the information is again transmitted to the NTS. The NTS reacts by inhibiting parasympathetic and activating sympathetic activities. The sympathetic system releases norepinephrine which acts on the SA node to increase heart rate; on cardiac myocytes to increase stroke volume and on smooth muscle cells of blood vessels to cause vasoconstriction. Together, these events rapidly bring UP blood pressure levels back to normal.
Baroreflex is a short-term response to sudden changes of blood pressure resulted from everyday activities and emotional states. If hypertension or hypotension persists for a long period of time, the baroreceptors will reset to the “new normal” levels. In hypertensive patients for example, baroreflex mechanism is adjusted to a higher “normal” pressure and therefore MAINTAINS hypertension rather than suppresses it.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.

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yt:quality=high acetylcholine ACh anatomy animated animation ans autonomic baroreceptor baroreceptors reset baroreflex biofeedback biology blood pressure blood vessels brain cardiology cardiovascular circulation circulatory system conditions disease disorder efferent heart control heart rate medical medulla NE negative feedback loop neural neuronal norepinephrine NTS parasympathetic pathway PSNS resetting SA node SNS sympathetic vascular system vasodilation visceral reflex

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Alila Medical Media . 2018-05-29
Help us make more videos like this! Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia
Thank you so much!
121 2 . Reply
clash with aloosh . 2019-04-19
God pless you
Alila is my love And my life ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤
121 2 . Reply
mera ahmed . 2019-04-16
Thank you so much
121 2 . Reply
#Chaze . 2019-03-11
Voice is annoying.
121 2 . Reply
Aurithra Barua . 2019-01-24
That's voice is just so much annoying.
But the animation along with the process was good.
121 2 . Reply
وداد باز عبد القادر . 2019-01-05
Thanks 😁😁😁 it's so benefit for me .... I was need it 🙂☺
121 2 . Reply
Way Of Light . 2018-12-07
software voice is disturbing
121 2 . Reply
OMNIVAS BEJUGAM . 2018-11-30
It's great
121 2 . Reply
BoF I . 2018-11-16
The video is good but the voice is soo annoying 🤕
121 2 . Reply
tarzan sabor . 2018-11-12
Thank Very much!
121 2 . Reply
urwa imran . 2018-11-10
I can't ever thank you enough. God bless you.
121 2 . Reply
puzz88 . 2018-11-05
This is out of the scope of the video, but is there a way to reverse the new hypertensive normal after chronic hypertension?
121 2 . Reply
จิดาภา อัญชลีธรรม . 2018-10-04
That’s a good video.Thank you so much.
121 2 . Reply
adam parker1 . 2018-09-21
is a 3 minute voiceover really too much to ask?
121 2 . Reply
leo A . 2018-09-05
this helped thanks!
121 2 . Reply
Izotope Panadol . 2018-08-16
Muita Boa a aula # Moçambique
121 2 . Reply
Geraldine Valencia Alvarez . 2018-04-30
I really love your videos. Thank you so much.
121 2 . Reply
Hypnos Stratagem . 2018-03-24
Great video.
121 2 . Reply
shizhe cheng . 2018-01-28
NTS?what's that
121 2 . Reply
Borat Sagdiyev . 2018-01-27
Still has less of a monotonous voice than my prof
121 2 . Reply
Mirza Aminur Rahaman . 2018-01-22
Please....Make a video on Sympathetic and Parasympathetic Nervous system
121 2 . Reply
Aditya T . 2018-01-09
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AMAH . 2017-12-29
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كاظم جاويد. الشبلاوي . 2017-12-22
121 2 . Reply
Ayendri Kabiraj . 2017-12-16
can u plz xplain brain brigde reflx
121 2 . Reply
PrecXx B. . 2017-11-05
121 2 . Reply
Mostafa Banhawy . 2017-11-03
Heard that recent studies disagree with this mechanism and it's effect. On bl.p
121 2 . Reply
Subramanian Narayanan . 2017-10-29
Why you are not saying cardiac center than nts
121 2 . Reply
Uzair Khan . 2017-09-24
what will be the effect vasodilator and vasoconstrictor drug
121 2 . Reply
Sanjay Patel . 2017-07-17
What effects are observed when the body is inverted such as during certain yoga and gymnastic exercises?
Heard that the baroreflex mediated by the carotid sinuses gets 'stimulated' by inversion and thereby produces a reduction of BP; this effect is said to become sustained with repetition of the exercises.
121 2 . Reply
HuiLing Jill Yang . 2017-06-19
121 2 . Reply
SRIKANTH PN . 2017-06-13
Good video
121 2 . Reply
ilovecanines . 2017-05-09
Would be much better without the computerized voice.
121 2 . Reply
Omar Ghoniem . 2017-04-05
thank you very much for understanding this mechanism 😊😊
121 2 . Reply
thanks so much, this really help me have a better understanding of how it works
121 2 . Reply
marim mohamed . 2017-02-27
121 2 . Reply
arpit porwal . 2017-02-07
good job
121 2 . Reply
PRONAB DEY . 2016-12-12
121 2 . Reply
bader alyousef . 2016-10-13
amazing work
121 2 . Reply